Blood The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro
نویسندگان
چکیده
*Guillaume Deplaine,1-3 *Innocent Safeukui,1,2 Fakhri Jeddi,3 François Lacoste,4 Valentine Brousse,5 Sylvie Perrot,1,2 Sylvestre Biligui,3,6 Micheline Guillotte,1,2 Corinne Guitton,7 Safi Dokmak,8 Béatrice Aussilhou,8 Alain Sauvanet,8 Dominique Cazals Hatem,9 François Paye,10 Marc Thellier,3,6 Dominique Mazier,3,6 Geneviève Milon,11 Narla Mohandas,12 Odile Mercereau-Puijalon,1,2 Peter H. David,1,2 and Pierre A. Buffet3,6
منابع مشابه
The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro.
Retention of poorly deformable red blood cells (RBCs) by the human spleen has been recognized as a critical determinant of pathogenesis in hereditary spherocytosis, malaria, and other RBC disorders. Using an ex vivo perfusion system, we had previously shown that retention of Plasmodium falciparum-infected RBCs (Pf-RBCs) occur in the splenic red pulp, upstream from the sinus wall. To experimenta...
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